TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T62815 UDP-glucuronosyltransferase 2B7 D01XYJ Zidovudine Approved 35370 C10H13N5O4 267.24 CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] Ki = 150000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 B5AZJ9 (1S)-4-Methylindan-1-ol Investigative 11615192 C10H12O 148.2 CC1=C2CC[C@@H](C2=CC=C1)O IC50 = 179000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 B7QG8K (R)-1-(Naphthalen-1-yl)ethanol Investigative 6976567 C12H12O 172.22 C[C@H](C1=CC=CC2=CC=CC=C21)O IC50 = 130000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BA81CY 1-Naphthalenol, 1,2,3,4-tetrahydro-5,7-dimethyl-, (1S)- Investigative 11636907 C12H16O 176.25 CC1=CC(=C2CCC[C@@H](C2=C1)O)C IC50 = 166000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BDT8S6 (4S)-6-Methyl-3,4-dihydro-2H-1-benzopyran-4-ol Investigative 12328974 C10H12O2 164.2 CC1=CC2=C(C=C1)OCC[C@@H]2O IC50 = 182000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BG1H7I Epiestriol Investigative 68929 C18H24O3 288.4 C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)O Ki = 162000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BJI0G5 (R)-(+)-1-(2-Naphthyl)ethanol Investigative 6976569 C12H12O 172.22 C[C@H](C1=CC2=CC=CC=C2C=C1)O IC50 = 79000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BPQZ97 5,7-Dimethyltetralin-1-ol Investigative 15148407 C12H16O 176.25 CC1=CC(=C2CCCC(C2=C1)O)C Ki = 101000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BT1F8G (S)-(-)-1-(2-Naphthyl)ethanol Investigative 6976568 C12H12O 172.22 C[C@@H](C1=CC2=CC=CC=C2C=C1)O IC50 = 105000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BU6K2M (Rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol Investigative 12328973 C10H12O2 164.2 CC1=CC2=C(C=C1)OCCC2O Ki = 113000 nM Poor binder T62815 UDP-glucuronosyltransferase 2B7 BVI8N1 1-Naphthalenol, 1,2,3,4-tetrahydro-5,7-dimethyl-, (1R)- Investigative 11658372 C12H16O 176.25 CC1=CC(=C2CCC[C@H](C2=C1)O)C IC50 = 158000 nM Poor binder