Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59537 | Target Info | |||
| Target Name | Membrane-associated kinase (PKMYT1) | ||||
| Synonyms |
Myt1 kinase; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; MYT1
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| Target Type | Literature-reported Target | ||||
| Gene Name | PKMYT1 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
TYRPHOSTIN AG-1478
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Investigative | Compound Info | ||
| Synonyms |
AG-1478; 153436-53-4; Tyrphostin AG 1478; N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine; 175178-82-2; Tyrphostin AG-1478; 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline; AG 1478; AG1478; TYRPHOSTIN; 4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-; UNII-SUH0SEZ9HY; SUH0SEZ9HY; AG-1478 hydrochloride; AG-1478 (Tyrphostin AG-1478); CHEMBL7917; CHEBI:75404; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine; NSC-693255; AK-63142; N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine; BRD6408; BRD-6408; SR-01000076156; NSC693255
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| Activity |
IC50 = 55000 nM
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[1] | |||
| Compound Name |
2-Amino-3-phenyl-5-(pyridin-4-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
GSK625137A; CHEMBL230911; SCHEMBL5305618; BDBM27475; HMS3303A20; HMS3305D21; Amino-substituted diarylbenzamide, 8p; NCGC00242156-01; 2-amino-3-phenyl-5-pyridin-4-ylbenzamide; AB01092095-01
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| Activity |
IC50 = 57990 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II. Bioorg Med Chem. 2018 Aug 7;26(14):4014-4024. | ||||
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