Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ZH1U
|
|||
| Former ID |
DNC005110
|
|||
| Drug Name |
Tyrphostin ag-1478
|
|||
| Synonyms |
AG-1478; 153436-53-4; Tyrphostin AG 1478; N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine; 175178-82-2; Tyrphostin AG-1478; 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline; AG 1478; AG1478; TYRPHOSTIN; 4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-; UNII-SUH0SEZ9HY; SUH0SEZ9HY; AG-1478 hydrochloride; AG-1478 (Tyrphostin AG-1478); CHEMBL7917; CHEBI:75404; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine; NSC-693255; AK-63142; N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine; BRD6408; BRD-6408; SR-01000076156; NSC693255
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H14ClN3O2
|
|||
| Canonical SMILES |
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
|
|||
| InChI |
1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
|
|||
| InChIKey |
GFNNBHLJANVSQV-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 153436-53-4
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
523974, 3267095, 5600223, 8033257, 8151403, 11111880, 11114011, 11120225, 11120713, 11121201, 11121455, 11121935, 11147308, 11362524, 11365086, 11367648, 11370319, 11370320, 11373249, 11375810, 11382272, 11437777, 12024897, 14801206, 17405683, 24278735, 26527902, 26752149, 26752150, 26759702, 29221232, 47290912, 47290913, 47588775, 47588776, 47662031, 48184767, 48258972, 49635532, 50104794, 50104795, 53778233, 53787589, 53800470, 57321117, 80516749, 85231256, 85267415, 85787241, 85787738
|
|||
| ChEBI ID |
CHEBI:75404
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4862). | |||
| REF 2 | Use of a pharmacophore model for the design of EGFR tyrosine kinase inhibitors: isoflavones and 3-phenyl-4(1H)-quinolones. J Med Chem. 1999 Mar 25;42(6):1018-26. | |||
| REF 3 | Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5389-94. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.