Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T37505 | Target Info | |||
| Target Name | Striatum-specific G-protein coupled receptor (GPR88) | ||||
| Synonyms |
STRG; Probable G-protein coupled receptor 88
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| Target Type | Literature-reported Target | ||||
| Gene Name | GPR88 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(1R,2S)-N-[(1R)-2-Hydroxy-1-naphthalen-2-ylethyl]-2-phenylcyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3403795; BDBM50064766
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| Activity |
EC50 ~ 81000 nM
|
[1] | |||
| Compound Name |
(1S,2R)-N-[(1R)-2-Hydroxy-1-naphthalen-2-ylethyl]-2-phenylcyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3403796; BDBM50064767
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| Activity |
EC50 ~ 110000 nM
|
[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(1R,2R)-N-[(1R)-2-Hydroxy-1-naphthalen-2-ylethyl]-2-phenylcyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3403794; BDBM50064765
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|
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| Activity |
EC50 > 270000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1448-52. | ||||
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