Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T24595 | Target Info | |||
| Target Name | Acrosin (ACR) | ||||
| Synonyms |
ACRS
Click to Show/Hide
|
||||
| Target Type | Literature-reported Target | ||||
| Gene Name | ACR | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 12 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-(2-Hydroxypropyl)-3-phenyl-1H-pyrazole-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397954; BDBM50436591; AKOS005883797
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
Ethyl 5-[4-[(2-chlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287437; BDBM50018965
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[2] | |||
| Compound Name |
Methyl N-[6-[bis(3-methylbutyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023317; BDBM50382108
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[3] | |||
| Compound Name |
1-[6-[(2-Fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316070; BDBM50424443
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[4] | |||
| Compound Name |
N-(2-Hydroxyethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397958; KS-00003I5A; BDBM50436618; HTS002902; MFCD28041869; ZINC96272556; AKOS025392565; BS-4780; N-(2-Hydroxyethyl)-5-(4-methoxyphenyl)-4H-pyrazole-3-carboxamide
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|
||||
| Activity |
IC50 = 90000 nM
|
[1] | |||
| Compound Name |
5-[4-(Diaminomethylideneamino)phenyl]-N-(1-hydroxypropan-2-yl)-1,2-oxazole-3-carboxamide;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287442; BDBM50018970
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
5-[4-(Diaminomethylideneamino)phenyl]-N-propan-2-yl-1,2-oxazole-3-carboxamide;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287441; BDBM50018969
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Ethyl 3-[4-(diaminomethylideneamino)phenyl]-1H-pyrazole-5-carboxylate;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596569
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-[4-(Diaminomethylideneamino)phenyl]-1H-pyrazole-5-carboxylic acid;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596570
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Ethyl 3-[4-[(2-chlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834501; LJG-5l; BDBM50354875
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[5] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-ethoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911232; BDBM50356306
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[6] | |||
| Compound Name |
Ethyl 5-[4-[(4-fluorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287438; BDBM50018966
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 129 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-ethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911231; BDBM50356307
Click to Show/Hide
|
||||
| Activity |
IC50 = 210000 nM
|
[6] | |||
| Compound Name |
Ethyl 5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287439; BDBM50018967
Click to Show/Hide
|
||||
| Activity |
IC50 = 240000 nM
|
[2] | |||
| Compound Name |
1-[6-(Benzylsulfamoyl)-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316076; BDBM50424437
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000 nM
|
[4] | |||
| Compound Name |
Methyl N-[6-[(2-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022136; BDBM50382090
Click to Show/Hide
|
||||
| Activity |
IC50 = 310000 nM
|
[3] | |||
| Compound Name |
3-(4-Bromophenyl)-N-(2-hydroxypropyl)-1H-pyrazole-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397948; BDBM50436597
Click to Show/Hide
|
||||
| Activity |
IC50 = 330000 nM
|
[1] | |||
| Compound Name |
1-[6-[(3,5-Difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316073; BDBM50424440
Click to Show/Hide
|
||||
| Activity |
IC50 = 340000 nM
|
[4] | |||
| Compound Name |
Ethyl 5-[4-[(4-chlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287440; BDBM50018968
Click to Show/Hide
|
||||
| Activity |
IC50 = 380000 nM
|
[2] | |||
| Compound Name |
3-(4-Bromophenyl)-N-(3-hydroxypropyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397947; BDBM50436598
Click to Show/Hide
|
||||
| Activity |
IC50 = 380000 nM
|
[1] | |||
| Compound Name |
5-(2,4-Dichlorophenyl)isoxazole-3-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023319; BDBM50382109; 3-Isoxazolecarboxaldehyde, 5-(2,4-dichlorophenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 390000 nM
|
[2] | |||
| Compound Name |
N-(2-Hydroxyethyl)-3-(4-methoxyphenyl)-N-methyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316083; BDBM50424449
Click to Show/Hide
|
||||
| Activity |
IC50 = 410000 nM
|
[1] | |||
| Compound Name |
Ethyl 3-[4-[(2,4-dichlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834503; BDBM50354877
Click to Show/Hide
|
||||
| Activity |
IC50 = 440000 nM
|
[7] | |||
| Compound Name |
Ethyl 5-(4-benzamidophenyl)-1,2-oxazole-3-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287436; BDBM50018964
Click to Show/Hide
|
||||
| Activity |
IC50 = 460000 nM
|
[2] | |||
| Compound Name |
Methyl N-[6-(propan-2-ylsulfamoyl)-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023314; BDBM50382105
Click to Show/Hide
|
||||
| Activity |
IC50 = 470000 nM
|
[3] | |||
| Compound Name |
Ethyl 3-[4-[(2-phenylacetyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834509; BDBM50354883
Click to Show/Hide
|
||||
| Activity |
IC50 = 470000 nM
|
[7] | |||
| Compound Name |
3-(4-Bromophenyl)-N-(2-hydroxyethyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397945; BDBM50436600
Click to Show/Hide
|
||||
| Activity |
IC50 = 530000 nM
|
[1] | |||
| Compound Name |
N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(dipentylamino)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316081; BDBM50424451
Click to Show/Hide
|
||||
| Activity |
IC50 = 540000 nM
|
[4] | |||
| Compound Name |
N-(3-Hydroxypropyl)-3-phenyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397953; BDBM50436592; AKOS009213995
Click to Show/Hide
|
||||
| Activity |
IC50 = 540000 nM
|
[1] | |||
| Compound Name |
N-(2-Hydroxyethyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397938; BDBM50436607
Click to Show/Hide
|
||||
| Activity |
IC50 = 760000 nM
|
[1] | |||
| Compound Name |
N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397944; BDBM50436601
Click to Show/Hide
|
||||
| Activity |
IC50 = 760000 nM
|
[1] | |||
| Compound Name |
N-(3-Hydroxypropyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397940; BDBM50436605
Click to Show/Hide
|
||||
| Activity |
IC50 = 780000 nM
|
[1] | |||
| Compound Name |
N-(2-Hydroxyethyl)-N-methyl-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397942; BDBM50436603
Click to Show/Hide
|
||||
| Activity |
IC50 = 790000 nM
|
[1] | |||
| Compound Name |
Ethyl 3-[4-[(4-methoxybenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834507; BDBM50354881
Click to Show/Hide
|
||||
| Activity |
IC50 = 800000 nM
|
[7] | |||
| Compound Name |
3-(4-Bromophenyl)-N-(1-hydroxypropan-2-yl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397949; BDBM50436596
Click to Show/Hide
|
||||
| Activity |
IC50 = 880000 nM
|
[1] | |||
| Compound Name |
N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-phenyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397957; BDBM50436619
Click to Show/Hide
|
||||
| Activity |
IC50 = 940000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-(benzylsulfamoyl)-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023306; BDBM50382099
Click to Show/Hide
|
||||
| Activity |
IC50 = 1030000 nM
|
[3] | |||
| Compound Name |
1-[6-[(2-Chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316077; BDBM50424455
Click to Show/Hide
|
||||
| Activity |
IC50 = 1060000 nM
|
[4] | |||
| Compound Name |
2-[Bis(3-methylbutyl)amino]-N-(6-bromo-1,3-benzothiazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316080; BDBM50424452
Click to Show/Hide
|
||||
| Activity |
IC50 = 1090000 nM
|
[4] | |||
| Compound Name |
N,N-Bis(2-hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397933; BDBM50436612
Click to Show/Hide
|
||||
| Activity |
IC50 = 1210000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-[benzyl(methyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023318; BDBM50382113
Click to Show/Hide
|
||||
| Activity |
IC50 = 1250000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-[(2,4-dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022141; BDBM50382095
Click to Show/Hide
|
||||
| Activity |
IC50 = 1270000 nM
|
[3] | |||
| Compound Name |
N-(3-Hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316085; BDBM50424447
Click to Show/Hide
|
||||
| Activity |
IC50 = 1430000 nM
|
[4] | |||
| Compound Name |
3-(4-Bromophenyl)-N,N-bis(2-hydroxyethyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397946; BDBM50436599
Click to Show/Hide
|
||||
| Activity |
IC50 = 1520000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-[(2,4-difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023308; BDBM50382111
Click to Show/Hide
|
||||
| Activity |
IC50 = 1550000 nM
|
[3] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911235; BDBM50356303
Click to Show/Hide
|
||||
| Activity |
IC50 = 1580000 nM
|
[6] | |||
| Compound Name |
Methyl N-[6-[(3,4-difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023309; BDBM50382101
Click to Show/Hide
|
||||
| Activity |
IC50 = 1590000 nM
|
[3] | |||
| Compound Name |
1-[6-(Hexylsulfamoyl)-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316078; BDBM50424454
Click to Show/Hide
|
||||
| Activity |
IC50 = 1620000 nM
|
[4] | |||
| Compound Name |
Methyl N-[6-[(4-bromophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022138; BDBM50382092
Click to Show/Hide
|
||||
| Activity |
IC50 = 1640000 nM
|
[3] | |||
| Compound Name |
N,N-Bis(2-hydroxyethyl)-3-phenyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397952; BDBM50436593; AKOS010485850
Click to Show/Hide
|
||||
| Activity |
IC50 = 1700000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-(butylsulfamoyl)-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023315; BDBM50382106
Click to Show/Hide
|
||||
| Activity |
IC50 = 1770000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-(hexylsulfamoyl)-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023316; BDBM50382107
Click to Show/Hide
|
||||
| Activity |
IC50 = 1800000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-[(3-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023310; BDBM50382102
Click to Show/Hide
|
||||
| Activity |
IC50 = 1810000 nM
|
[3] | |||
| Compound Name |
N-(2-Hydroxypropyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397941; BDBM50436604
Click to Show/Hide
|
||||
| Activity |
IC50 = 1830000 nM
|
[1] | |||
| Compound Name |
N-(1-Hydroxy-2-methylpropan-2-yl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397935; BDBM50436610
Click to Show/Hide
|
||||
| Activity |
IC50 = 1875000 nM
|
[1] | |||
| Compound Name |
N-(2-Hydroxyethyl)-N-methyl-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397934; BDBM50436611
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[1] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911218; CBMicro_021242; CCG-8851; BDBM50356320; BIM-0021246.P001; SR-01000210225; SR-01000210225-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 2060000 nM
|
[6] | |||
| Compound Name |
N-[2-(2-Hydroxyethoxy)ethyl]-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397936; BDBM50436609
Click to Show/Hide
|
||||
| Activity |
IC50 = 2070000 nM
|
[1] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911199; BDBM50356321
Click to Show/Hide
|
||||
| Activity |
IC50 = 2210000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-phenoxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911245; BDBM50356325
Click to Show/Hide
|
||||
| Activity |
IC50 = 2300000 nM
|
[6] | |||
| Compound Name |
Propan-2-yl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911242; BDBM50356322
Click to Show/Hide
|
||||
| Activity |
IC50 = 2350000 nM
|
[6] | |||
| Compound Name |
Ethyl 3-[4-[(4-fluorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834499; BDBM50354873
Click to Show/Hide
|
||||
| Activity |
IC50 = 2400000 nM
|
[7] | |||
| Compound Name |
Methyl N-[6-[(4-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022137; BDBM50382091
Click to Show/Hide
|
||||
| Activity |
IC50 = 2400000 nM
|
[3] | |||
| Compound Name |
N,N-Bis(2-hydroxyethyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397939; BDBM50436606
Click to Show/Hide
|
||||
| Activity |
IC50 = 2400000 nM
|
[1] | |||
| Compound Name |
Ethyl 3-[4-[(2-bromobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834505; BDBM50354879
Click to Show/Hide
|
||||
| Activity |
IC50 = 2400000 nM
|
[7] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2,4,6-trimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911228; BDBM50356310
Click to Show/Hide
|
||||
| Activity |
IC50 = 2450000 nM
|
[6] | |||
| Compound Name |
1-[6-[(3,5-Dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316072; BDBM50424441
Click to Show/Hide
|
||||
| Activity |
IC50 = 2450000 nM
|
[4] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-3,5-dinitrobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911230; NSC719391; BDBM50356308; NSC-719391
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[6] | |||
| Compound Name |
3-Methylbutyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911244; BDBM50356324
Click to Show/Hide
|
||||
| Activity |
IC50 = 2510000 nM
|
[6] | |||
| Compound Name |
N-(2-Hydroxyethyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397929; BDBM50436616
Click to Show/Hide
|
||||
| Activity |
IC50 = 2700000 nM
|
[1] | |||
| Compound Name |
N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(dibutylamino)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316079; BDBM50424453
Click to Show/Hide
|
||||
| Activity |
IC50 = 2780000 nM
|
[4] | |||
| Compound Name |
N-(2-Hydroxyethyl)-3-phenyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397951; BDBM50436594; AKOS005832714
Click to Show/Hide
|
||||
| Activity |
IC50 = 2800000 nM
|
[1] | |||
| Compound Name |
N-(2-Hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397932; BDBM50436613
Click to Show/Hide
|
||||
| Activity |
IC50 = 2950000 nM
|
[1] | |||
| Compound Name |
Ethyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911240; BDBM50356298
Click to Show/Hide
|
||||
| Activity |
IC50 = 2990000 nM
|
[6] | |||
| Compound Name |
N-(1-Hydroxypropan-2-yl)-3-phenyl-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397956; BDBM50436620; AKOS009244515
Click to Show/Hide
|
||||
| Activity |
IC50 = 3000000 nM
|
[1] | |||
| Compound Name |
N-(3-Hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397931; BDBM50436614
Click to Show/Hide
|
||||
| Activity |
IC50 = 3070000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-[(4-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023305; BDBM50382098
Click to Show/Hide
|
||||
| Activity |
IC50 = 3180000 nM
|
[3] | |||
| Compound Name |
Ethyl 1-(2,4-dichlorobenzoyl)indazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316087; BDBM50424445
Click to Show/Hide
|
||||
| Activity |
IC50 = 3240000 nM
|
[4] | |||
| Compound Name |
Methyl N-[6-[(4-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022143; BDBM50382110
Click to Show/Hide
|
||||
| Activity |
IC50 = 3290000 nM
|
[3] | |||
| Compound Name |
Ethyl 3-[4-(2-phenylbutanoylamino)phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834510; BDBM50354884
Click to Show/Hide
|
||||
| Activity |
IC50 = 3300000 nM
|
[7] | |||
| Compound Name |
Ethyl 3-[4-[[4-(chloromethyl)benzoyl]amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834508; BDBM50354882
Click to Show/Hide
|
||||
| Activity |
IC50 = 3310000 nM
|
[7] | |||
| Compound Name |
Propyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911241; BDBM50356297
Click to Show/Hide
|
||||
| Activity |
IC50 = 3310000 nM
|
[6] | |||
| Compound Name |
Ethyl 3-[4-[(4-chlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834502; BDBM50354876
Click to Show/Hide
|
||||
| Activity |
IC50 = 3310000 nM
|
[7] | |||
| Compound Name |
1-(2,4-Dichlorobenzoyl)-N-methylindazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316088; BDBM50424444
Click to Show/Hide
|
||||
| Activity |
IC50 = 3780000 nM
|
[4] | |||
| Compound Name |
3,4-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911223; BDBM50356315
Click to Show/Hide
|
||||
| Activity |
IC50 = 3800000 nM
|
[6] | |||
| Compound Name |
4-(Chloromethyl)-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911227; BDBM50356311
Click to Show/Hide
|
||||
| Activity |
IC50 = 3840000 nM
|
[6] | |||
| Compound Name |
Ethyl 3-[4-[(2,6-difluorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834500; BDBM50354874
Click to Show/Hide
|
||||
| Activity |
IC50 = 3980000 nM
|
[7] | |||
| Compound Name |
Methyl N-[6-[(3,4-dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022142; BDBM50382096
Click to Show/Hide
|
||||
| Activity |
IC50 = 4020000 nM
|
[3] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-nitrophenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911251; BDBM50356331
Click to Show/Hide
|
||||
| Activity |
IC50 = 4200000 nM
|
[6] | |||
| Compound Name |
Ethyl 3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834504; BDBM50354878
Click to Show/Hide
|
||||
| Activity |
IC50 = 4800000 nM
|
[7] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methylpiperidin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911238; BDBM50356300
Click to Show/Hide
|
||||
| Activity |
IC50 = 4980000 nM
|
[6] | |||
| Compound Name |
Methyl N-[6-[(3-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023304; BDBM50382097
Click to Show/Hide
|
||||
| Activity |
IC50 = 5060000 nM
|
[3] | |||
| Compound Name |
N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(4-pentylpiperazin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316082; BDBM50424450
Click to Show/Hide
|
||||
| Activity |
IC50 = 5080000 nM
|
[4] | |||
| Compound Name |
N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397937; BDBM50436608
Click to Show/Hide
|
||||
| Activity |
IC50 = 5220000 nM
|
[1] | |||
| Compound Name |
1-(2-Hydroxyethyl)-3-[6-[(3-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316075; BDBM50424438
Click to Show/Hide
|
||||
| Activity |
IC50 = 5450000 nM
|
[4] | |||
| Compound Name |
N,N-Bis(2-hydroxyethyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397930; BDBM50436615
Click to Show/Hide
|
||||
| Activity |
IC50 = 5600000 nM
|
[1] | |||
| Compound Name |
2,4-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911221; BDBM50356317
Click to Show/Hide
|
||||
| Activity |
IC50 = 5630000 nM
|
[6] | |||
| Compound Name |
N,N-Bis(2-hydroxyethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316084; BDBM50424448
Click to Show/Hide
|
||||
| Activity |
IC50 = 5730000 nM
|
[4] | |||
| Compound Name |
Methyl N-[6-[(2-chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022139; BDBM50382093
Click to Show/Hide
|
||||
| Activity |
IC50 = 5750000 nM
|
[3] | |||
| Compound Name |
Ethyl 3-[4-(3-chloropropanoylamino)phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834550; BDBM50354869
Click to Show/Hide
|
||||
| Activity |
IC50 = 5760000 nM
|
[7] | |||
| Compound Name |
2,6-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911222; BDBM50356316
Click to Show/Hide
|
||||
| Activity |
IC50 = 5960000 nM
|
[6] | |||
| Compound Name |
N-[2-(2-Hydroxyethoxy)ethyl]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397928; BDBM50436617
Click to Show/Hide
|
||||
| Activity |
IC50 = 6020000 nM
|
[1] | |||
| Compound Name |
1-(2-Hydroxyethyl)-3-[6-[(2-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316074; BDBM50424439
Click to Show/Hide
|
||||
| Activity |
IC50 = 6040000 nM
|
[4] | |||
| Compound Name |
2-Chloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911219; BDBM50356319
Click to Show/Hide
|
||||
| Activity |
IC50 = 6300000 nM
|
[6] | |||
| Compound Name |
3-Chloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911220; BDBM50356318
Click to Show/Hide
|
||||
| Activity |
IC50 = 7000000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911229; BDBM50356309
Click to Show/Hide
|
||||
| Activity |
IC50 = 7050000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-fluorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911225; BDBM50356313
Click to Show/Hide
|
||||
| Activity |
IC50 = 7110000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2,6-difluorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911226; BDBM50356312
Click to Show/Hide
|
||||
| Activity |
IC50 = 7180000 nM
|
[6] | |||
| Compound Name |
1-(2-Hydroxyethyl)-3-[6-[(3-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316071; BDBM50424442
Click to Show/Hide
|
||||
| Activity |
IC50 = 7320000 nM
|
[4] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-piperidin-1-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911236; BDBM50356302
Click to Show/Hide
|
||||
| Activity |
IC50 = 7410000 nM
|
[6] | |||
| Compound Name |
Methyl N-[6-[(3-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023312; BDBM50382104
Click to Show/Hide
|
||||
| Activity |
IC50 = 7500000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-[(4-chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022140; BDBM50382094
Click to Show/Hide
|
||||
| Activity |
IC50 = 7520000 nM
|
[3] | |||
| Compound Name |
2-Bromo-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911224; BDBM50356314
Click to Show/Hide
|
||||
| Activity |
IC50 = 7630000 nM
|
[6] | |||
| Compound Name |
Ethyl 3-[4-[(2,2,2-trifluoroacetyl)amino]phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834549; BDBM50354868
Click to Show/Hide
|
||||
| Activity |
IC50 = 7900000 nM
|
[7] | |||
| Compound Name |
Ethyl 3-(4-benzamidophenyl)-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834553; BDBM50354872
Click to Show/Hide
|
||||
| Activity |
IC50 = 8000000 nM
|
[7] | |||
| Compound Name |
Methyl N-[6-[(2-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023311; BDBM50382103
Click to Show/Hide
|
||||
| Activity |
IC50 = 8420000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-[(2,5-dimethylphenyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022135; BDBM50382089
Click to Show/Hide
|
||||
| Activity |
IC50 = 8860000 nM
|
[3] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(3-methylphenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911247; BDBM50356327
Click to Show/Hide
|
||||
| Activity |
IC50 = 8920000 nM
|
[6] | |||
| Compound Name |
N-(2-Hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316086; BDBM50424446
Click to Show/Hide
|
||||
| Activity |
IC50 = 8920000 nM
|
[4] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methylphenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911248; BDBM50356328
Click to Show/Hide
|
||||
| Activity |
IC50 = 8980000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911233; BDBM50356305
Click to Show/Hide
|
||||
| Activity |
IC50 = 9000000 nM
|
[6] | |||
| Compound Name |
N-[2-(2-Hydroxyethoxy)ethyl]-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397943; BDBM50436602
Click to Show/Hide
|
||||
| Activity |
IC50 = 9100000 nM
|
[1] | |||
| Compound Name |
4-[4-(5-Ethoxycarbonyl-1H-pyrazol-3-yl)anilino]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834551; BDBM50354870
Click to Show/Hide
|
||||
| Activity |
IC50 = 9250000 nM
|
[7] | |||
| Compound Name |
Methyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911239; BDBM50356299
Click to Show/Hide
|
||||
| Activity |
IC50 = 9300000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(2-methylphenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911246; BDBM50356326
Click to Show/Hide
|
||||
| Activity |
IC50 = 9300000 nM
|
[6] | |||
| Compound Name |
2-(4-Chlorophenoxy)-N-[4-(diaminomethylideneamino)sulfonylphenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911249; BDBM50356329
Click to Show/Hide
|
||||
| Activity |
IC50 = 9350000 nM
|
[6] | |||
| Compound Name |
Butyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911243; BDBM50356323
Click to Show/Hide
|
||||
| Activity |
IC50 = 9500000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911234; BDBM50356304
Click to Show/Hide
|
||||
| Activity |
IC50 = 9580000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methoxyphenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911250; BDBM50356330
Click to Show/Hide
|
||||
| Activity |
IC50 = 9840000 nM
|
[6] | |||
| Compound Name |
N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(2-methylpiperidin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911237; BDBM50356301
Click to Show/Hide
|
||||
| Activity |
IC50 = 9900000 nM
|
[6] | |||
| Compound Name |
3-(4-Bromophenyl)-N-[2-(2-hydroxyethoxy)ethyl]-1H-pyrazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2397950; BDBM50436595
Click to Show/Hide
|
||||
| Activity |
IC50 = 10000000 nM
|
[1] | |||
| Compound Name |
Methyl N-[6-[[4-(trifluoromethyl)phenyl]methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023307; BDBM50382100
Click to Show/Hide
|
||||
| Activity |
IC50 = 10700000 nM
|
[3] | |||
| Compound Name |
Methyl N-[6-[(3,4-dimethoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2023313; BDBM50382112
Click to Show/Hide
|
||||
| Activity |
IC50 = 11500000 nM
|
[3] | |||
| Compound Name |
Ethyl 3-[4-(propanoylamino)phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834546; BDBM50354865
Click to Show/Hide
|
||||
| Activity |
IC50 = 14000000 nM
|
[7] | |||
| Compound Name |
Ethyl 3-[4-(butanoylamino)phenyl]-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834547; BDBM50354866
Click to Show/Hide
|
||||
| Activity |
IC50 = 17000000 nM
|
[7] | |||
| Compound Name |
5-[4-(5-Ethoxycarbonyl-1H-pyrazol-3-yl)anilino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834552; BDBM50354871
Click to Show/Hide
|
||||
| Activity |
IC50 = 17400000 nM
|
[7] | |||
| Compound Name |
Ethyl 3-(4-acetamidophenyl)-1H-pyrazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834545; BDBM50354864
Click to Show/Hide
|
||||
| Activity |
IC50 = 23000000 nM
|
[7] | |||
| Compound Name |
Ethyl 3-[4-[(4-methylbenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834506; BDBM50354880
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| Activity |
IC50 = 34600000 nM
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[7] | |||
| Compound Name |
Ethyl 3-[4-(pentanoylamino)phenyl]-1H-pyrazole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834548; BDBM50354867
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| Activity |
IC50 = 72000000 nM
|
[7] | |||
| Compound Name |
Tosyl-L-lysine chloromethyl ketone
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Investigative | Compound Info | ||
| Synonyms |
Tos-Lys-CH2Cl; Tosyllysyl chloromethyl ketone; N-alpha-p-Tosyl-L-lysine chloromethyl ketone; alpha-Tosyl-L-lysylchloromethyl ketone; BRN 2885388; CHEMBL466465; N-alpha-Tosyl-L-lysyl-chloromethylketone; N-[(1s)-5-Amino-1-(Chloroacetyl)pentyl]-4-Methylbenzenesulfonamide; n-[(3s)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide; N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide; p-Toluenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-, L-; tosyl-lysylchloromethane; Lopac-T-7254; Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-, (S)-; Tosyl-L-lysyl-chloromethane; C14H21ClN2O3S; Lopac0_001180; SCHEMBL200247; N-Tosyl-Lys-chloromethylketone; DTXSID7048459; ZINC1532775; BDBM50354886; Benzenesulfonamide, N-((1S)-5-amino-1-(chloroacetyl)pentyl)-4-methyl-; CCG-205254; DB08603; SDCCGSBI-0051147.P003; NCGC00016045-01; NCGC00162359-01; NCGC00162359-02; NCGC00162359-07; N.alpha.-pTosyl-L-lysine chloromethylketone; C00896; (-)-1-Chloro-3-tosylamido-7-amino-2-heptanone; Q27097802; Benzenesulfonamide, N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-; (S)-N-(7-amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide
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| Activity |
IC50 = 142600000 nM
|
[3] | |||
| Compound Name |
Tosyllysine chloromethyl ketone
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|
Investigative | Compound Info | ||
| Synonyms |
N-(7-amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide; Tosyllysyl chloromethane; Chlorotosylamidoaminoheptanone; p-Toluenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-, L-; Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-; SCHEMBL200245; CHEMBL2316089; 1-chloro-3-tosylamino-7-amino-2-heptanone; FT-0634224; N-(1-Chloro-7-amino-2-oxoheptane-3-yl)-p-toluenesulfonamide
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| Activity |
IC50 = 142600000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and acrosin inhibitory activities of 5-phenyl-1H-pyrazole-3-carboxylic acid amide derivatives. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4177-84. | ||||
| REF 2 | Design and synthesis of phenylisoxazole derivatives as novel human acrosin inhibitors. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2802-6. | ||||
| REF 3 | Synthesis and acrosin inhibitory activity of methyl 5-substituted-1H-benzo[d]imidazol-2-yl carbamate derivatives. Bioorg Med Chem Lett. 2012 May 15;22(10):3554-9. | ||||
| REF 4 | Design and synthesis of novel benzoheterocyclic derivatives as human acrosin inhibitors by scaffold hopping. Eur J Med Chem. 2013 Jan;59:176-82. | ||||
| REF 5 | Discovery of novel guanidinophenylpyrazole human acrosin inhibitors by molecular hybridization. Medchemcomm. 2014;5:1520-7. | ||||
| REF 6 | Synthesis and acrosin inhibitory activity of substituted 4-amino-N-(diaminomethylene) benzenesulfonamide derivatives. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6674-7. | ||||
| REF 7 | Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivatives. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5822-5. | ||||
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