TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T24595	Acrosin	B42HES	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-ethoxybenzamide	Investigative	57394478	C16H18N4O4S	362.4	CCOC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 130000 nM	Poor binder
T24595	Acrosin	B6TSQ3	5-[4-(Diaminomethylideneamino)phenyl]-N-(1-hydroxypropan-2-yl)-1,2-oxazole-3-carboxamide;hydrochloride	Investigative	90644234	C14H18ClN5O3	339.78	CC(CO)NC(=O)C1=NOC(=C1)C2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T24595	Acrosin	B78CGW	Methyl N-[6-[bis(3-methylbutyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70683504	C19H30N4O4S	410.5	CC(C)CCN(CCC(C)C)S(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC	IC50 = 63000 nM	Poor binder
T24595	Acrosin	B7C0YF	5-[4-(Diaminomethylideneamino)phenyl]-N-propan-2-yl-1,2-oxazole-3-carboxamide;hydrochloride	Investigative	90644233	C14H18ClN5O2	323.78	CC(C)NC(=O)C1=NOC(=C1)C2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T24595	Acrosin	B8BU6T	N-(2-Hydroxyethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide	Investigative	19508766	C13H15N3O3	261.279	COC1=CC=C(C=C1)C2=NNC(=C2)C(=O)NCCO	IC50 = 90000 nM	Poor binder
T24595	Acrosin	B8VG5Q	Ethyl 3-[4-(diaminomethylideneamino)phenyl]-1H-pyrazole-5-carboxylate;hydrochloride	Investigative	122182874	C13H16ClN5O2	309.75	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T24595	Acrosin	B9VD8H	Ethyl 5-[4-[(4-fluorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate	Investigative	60142639	C19H15FN2O4	354.3	CCOC(=O)C1=NOC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)F	IC50 = 140000 nM	Poor binder
T24595	Acrosin	BC2LE7	N-(2-Hydroxypropyl)-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	43418370	C13H15N3O2	245.28	CC(CNC(=O)C1=CC(=NN1)C2=CC=CC=C2)O	IC50 = 60000 nM	Poor binder
T24595	Acrosin	BF4JR1	Ethyl 3-[4-[(2-chlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	53484097	C19H16ClN3O3	369.8	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3Cl	IC50 = 110000 nM	Poor binder
T24595	Acrosin	BHT56W	1-[6-[(2-Fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569407	C17H18FN5O4S	407.4	C1=CC=C(C(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO)F	IC50 = 80000 nM	Poor binder
T24595	Acrosin	BSYF19	3-[4-(Diaminomethylideneamino)phenyl]-1H-pyrazole-5-carboxylic acid;hydrochloride	Investigative	122182876	C11H12ClN5O2	281.7	C1=CC(=CC=C1C2=NNC(=C2)C(=O)O)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T24595	Acrosin	BZ7JT6	Ethyl 5-[4-[(2-chlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate	Investigative	60142640	C19H15ClN2O4	370.8	CCOC(=O)C1=NOC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3Cl	IC50 = 60000 nM	Poor binder