Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T24373 | Target Info | |||
| Target Name | Lysosomal acid lipase (LIPA) | ||||
| Synonyms |
Sterol esterase; Lysosomal acid lipase/cholesteryl ester hydrolase; Lipase A; LIPA; LAL; Cholesteryl esterase; Acid cholesteryl ester hydrolase
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| Target Type | Successful Target | ||||
| Gene Name | LIPA | ||||
| Biochemical Class | Carboxylic ester hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3,3-Difluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-naphthalen-2-yl)-pentadecan-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL288982; BDBM50287474
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of alpha-difluoro and alpha-difluoro-beta-trifluoroketo-derivatives as potential inhibitors for Cholesterol Ester Hydrolase. Bioorg Med Chem Lett. 1996 Jul 23;6(14):1673-6. | ||||
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