Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T21782 | Target Info | |||
Target Name | Proliferating cell nuclear antigen (PCNA) | ||||
Synonyms |
Cyclin
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Target Type | Clinical trial Target | ||||
Gene Name | PCNA | ||||
UniProt ID |
Poor Binders of This Target (in total, 6 binders) | Download | Top | |||
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Compound Name |
2-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-N-phenylacetamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2348298; SCHEMBL16124455; BDBM50431451
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Compound Name |
N,N-Diethyl-2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2348295; SCHEMBL16124456; BDBM50431454
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Compound Name |
3,3'-Diiodo-L-thyronine
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Investigative | Compound Info | ||
Synonyms |
O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine; L-3,3'-Diiodothyronine; 3,3'-DEIODO-THYROXINE; 3,3'-Diiodothyronine, L-; (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid; 3,3'-Diiodothyronine; UNII-3L9U2Z4602; CHEMBL1236140; Tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-; MFCD01863378; 3L9U2Z4602; (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoic acid; EINECS 225-005-7; 3,3\\'-diiodo-L-thyronine; SCHEMBL935895; CTK2H8121; DTXSID80196697; 3,3'-Diiodo-L-thyronine (T2); 6334AB; ANW-53144; BDBM50431469; ZINC16051523; AKOS015918402; AS-57862; SC-43579; HY-129974; CS-0108953; 3,3'-Diiodo-L-thyronine (T2), 98% (CP); 604D415; A826975; L-tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-; Levothyroxine Impurity J (3,3'-L-Diiodothyronine); Q27104556; L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo- (9CI); Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-, L- (8CI)
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Compound Name |
Levothyroxine
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Investigative | Compound Info | ||
Synonyms |
L-thyroxine; thyroxine; thyroxin; Tetraiodothyronine; Thyrax; 3,3',5,5'-Tetraiodo-L-thyronine; synthroid; Thyratabs; Thyroxinal; Thyroxine iodine; Thyreoideum; Levothyroxin; (-)-Thyroxine; L-Thyroxin; 3,5,3',5'-Tetraiodo-L-thyronine; Thyroxine (l); Levothyroxine sodium; DL-Thyroxin; levothroid; Levoxyl; Thyroxine (VAN); eltroxin; 3,5,3',5'-Tetraiodothyronine; Laevothyroxinum; T4 (Hormone); L-3,5,3',5'-Tetraiodothyronine; Levothyroxinum (acid); Laevothyroxinum (acid); Thryroxine, l-; Oroxine; Tetramet; Thyroxine I 125; Levo-T; Forthyron (TN); Laevoxin; Thyroxevan; Synthroid sodium; NSC 36397; Levothyroxinum; 3,3',5,5''-Tetraiodo-L-thyronine; CCRIS 6739; Henning; HSDB 3108; 3,5,3'5'-Tetraiodo-L-thyronine; UNII-Q51BO43MG4; Prestwick_548; Thyro-Tabs; CHEMBL1624; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; C15H11I4NO4; Q51BO43MG4; 51-48-9 (free); MFCD00002595; NCGC00164336-01; L-Thyroxine, 97+%; DSSTox_CID_3214; DSSTox_RID_76927; DSSTox_GSID_23214; Eutirox; SMR000059176; Levothyroxine (BAN); EINECS 200-101-1; Levothyroxine [INN:BAN]; Synthroid (*Sodium salt*); BRN 2228515; SR-01000759430; NSC-36397; L-Tyrosine,; Spectrum_001076; CPD000059176; L-Thyroxine, free acid; SpecPlus_000871; Prestwick0_000403; Prestwick1_000403; Prestwick2_000403; Prestwick3_000403; Spectrum2_000573; Spectrum3_000611; Spectrum4_000128; Spectrum5_001500; Thyroxine, L- (8CI); bmse000923; Epitope ID:123889; T-3850; L-Thyroxine (T4) solution; BIDD:PXR0161; Levothroid (*Sodium salt*); SCHEMBL23098; BSPBio_000326; BSPBio_002142; KBioGR_000516; KBioSS_001556; MLS000028647; MLS002548901; DivK1c_006967; SPECTRUM1500774; SPBio_000386; SPBio_002265; BPBio1_000360; GTPL2635; DTXSID8023214; CTK2H7538; KBio1_001911; KBio2_001556; KBio2_004124; KBio2_006692; KBio3_001642; KS-00000HDI; HMS1569A08; HMS1921I06; HMS2090P18; HMS2092K12; HMS2096A08; HMS2233J18; HMS3259M11; HMS3713A08; L-Thyroxine, >=98% (HPLC); Pharmakon1600-01500774; ZINC3830993; Tox21_112101; Tox21_302156; BDBM50301375; CCG-38738; NSC757434; s2599; AKOS015905129; Tox21_112101_1; AC-7504; AM83594; CS-1819; DB00451; NC00485; NSC-757434; SDCCGMLS-0066571.P001; 3,3'',5,5''-tetraiodo-L-thyronine; 3,5,3'',5''-tetraiodo-L-thyronine; NCGC00094852-03; NCGC00164336-02; NCGC00164336-03; NCGC00164336-04; NCGC00164336-05; NCGC00164336-06; NCGC00255368-01; AC-10465; HY-18341; SBI-0051608.P002; AB0010528; DB-006261; SW196731-3; C01829; D08125; J10324; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-; AB00052176-08; AB00052176_09; AB00052176_10; 002T595; Q773449; SR-05000001567; SR-01000759430-2; SR-05000001567-1; BRD-K30685142-001-05-5; BRD-K30685142-001-08-9
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Compound Name |
2-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-1-piperidin-1-ylethanone
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2348296; SCHEMBL16124457; BDBM50431453
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Compound Name |
N-Butyl-2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2348297; BDBM50431452
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Activity |
IC50 ~ 50000 nM
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[1] | |||
Click to Show/Hide the Information of All Poor Binders |
References | Top | ||||
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REF 1 | Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis. Bioorg Med Chem. 2013 Apr 1;21(7):1972-7. |
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