Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T09133 | Target Info | |||
| Target Name | LIM domain kinase-2 (LIMK-2) | ||||
| Synonyms |
LIMK-2; LIM domain kinase 2
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| Target Type | Literature-reported Target | ||||
| Gene Name | LIMK2 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
5-[6-(2-Chloro-4-cyclopentyloxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-N-propyl-1,3-thiazol-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2070496; SCHEMBL4409238; BDBM50390778
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
CID 58688474
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2070495; SCHEMBL4407873; BDBM50390777; 5-[6-(2-chloro-4-pentan-3-yloxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-N-propyl-1,3-thiazol-2-amine
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8. | ||||
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