Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T00820 | Target Info | |||
Target Name | Inward rectifier potassium channel Kir6.2 (KCNJ11) | ||||
Synonyms |
Potassium channel, inwardly rectifying, subfamily J, member 11; KCNJ11; KATP channel (Kir6.2/SUR2A); Inward rectifier K+ channel Kir6.2; IKATP
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Target Type | Literature-reported Target | ||||
Gene Name | KCNJ11 | ||||
Biochemical Class | Inward rectifier potassium channel | ||||
UniProt ID |
Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
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Compound Name |
2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-butyramide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL296879; SCHEMBL7112438; BDBM50127796; N-[2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)naphthalen-1-yl]-2-methylbutanamide
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Activity |
EC50 = 177000 nM
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[1] |
References | Top | ||||
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REF 1 | Structure-activity relationship of a novel class of naphthyl amide KATP channel openers. Bioorg Med Chem Lett. 2003 May 19;13(10):1741-4. |
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