Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T00254 | Target Info | |||
| Target Name | V-erbA-related protein 1 (NR1D1) | ||||
| Synonyms |
THRAL; Rev-erbA-alpha; Nuclear receptor subfamily 1 group D member 1; HREV; EAR1; EAR-1
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| Target Type | Preclinical Target | ||||
| Gene Name | NR1D1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
5-[[(2-Fluorophenyl)methyl-(pyridin-3-ylmethyl)amino]methyl]thiophene-2-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381195; BDBM50434032
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| Activity |
EC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-(4-Chlorophenyl)-N-(1H-imidazol-2-ylmethyl)-N-(pyridin-3-ylmethyl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381213; BDBM50434024
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| Activity |
EC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-
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Investigative | Compound Info | ||
| Synonyms |
SR9011; SR-9011; CHEMBL1961797; GTPL8900; KS-00000TT2; BDBM50366239; CS-4668; DB14014; SB19005; SR 9011; NCGC00347956-01; AK547296; AS-55867; HY-16988; Q15410183
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| Activity |
EC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-(4-Chlorophenyl)-N-(pyridin-3-ylmethyl)-N-(1,3-thiazol-2-ylmethyl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381212; BDBM50434027
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| Activity |
EC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
SR9009; SR-9009; Stenabolic (SR9009); SR 9009; CHEMBL1961796; GTPL8901; EX-A726; BCP16215; BDBM50366238; MFCD29472236; s8692; AKOS027470307; CCG-269102; CS-4669; DB14013; SB19006; NCGC00384202-01; AC-30219; AK547297; AS-55859; HY-16989; J-690150; Q15410184
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| Activity |
EC50 ~ 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Optimized chemical probes for REV-ERBalpha. J Med Chem. 2013 Jun 13;56(11):4729-37. | ||||
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