TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T00254 V-erbA-related protein 1 B0Q4FP 5-[[(2-Fluorophenyl)methyl-(pyridin-3-ylmethyl)amino]methyl]thiophene-2-carbonitrile Investigative 71682941 C19H16FN3S 337.4 C1=CC=C(C(=C1)CN(CC2=CN=CC=C2)CC3=CC=C(S3)C#N)F EC50 ~ 50000 nM Poor binder T00254 V-erbA-related protein 1 BC5QP7 1-(4-Chlorophenyl)-N-(1H-imidazol-2-ylmethyl)-N-(pyridin-3-ylmethyl)methanamine Investigative 71682936 C17H17ClN4 312.8 C1=CC(=CN=C1)CN(CC2=CC=C(C=C2)Cl)CC3=NC=CN3 EC50 ~ 50000 nM Poor binder T00254 V-erbA-related protein 1 BI4US3 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl- Investigative 57394021 C23H31ClN4O3S 479 CCCCCNC(=O)N1CCC(C1)CN(CC2=CC=C(C=C2)Cl)CC3=CC=C(S3)[N+](=O)[O-] EC50 ~ 50000 nM Poor binder T00254 V-erbA-related protein 1 BRC37D 1-(4-Chlorophenyl)-N-(pyridin-3-ylmethyl)-N-(1,3-thiazol-2-ylmethyl)methanamine Investigative 71682791 C17H16ClN3S 329.8 C1=CC(=CN=C1)CN(CC2=CC=C(C=C2)Cl)CC3=NC=CS3 EC50 ~ 50000 nM Poor binder T00254 V-erbA-related protein 1 BZOH15 Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate Investigative 57394020 C20H24ClN3O4S 437.9 CCOC(=O)N1CCC(C1)CN(CC2=CC=C(C=C2)Cl)CC3=CC=C(S3)[N+](=O)[O-] EC50 ~ 50000 nM Poor binder