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| Protein General Information (TTD Target) |
Top |
| Full Name |
Ubiquitin isopeptidase Y (USP8)
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Preclinical
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Target Info
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| UniProt ID |
UBP8_HUMAN
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| Gene Name |
USP8
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
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PPI Info
|
[1] |
| Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
|
PPI Info
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[2] |
| References |
Top |
| REF 1 |
Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis. J Cancer Prev. 2015 Mar;20(1):57-63.
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| REF 2 |
The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types. Chem Biol. 2011 Dec 23;18(12):1550-61.
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