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Protein General Information (TTD Target) |
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Full Name |
TRAIL receptor 2 (TRAIL-R2)
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Clinical trial
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Target Info
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UniProt ID |
TR10B_HUMAN
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Gene Name |
TNFRSF10B
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Gene ID |
8795
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References |
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REF 1 |
Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells. Blood. 2005 Feb 1;105(3):1246-55.
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REF 2 |
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J. 1997 Sep 1;16(17):5386-97.
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REF 3 |
DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells. Mol Oncol. 2017 Dec;11(12):1733-1751.
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