Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Apoptosis mediating surface antigen FAS (FAS) | Clinical trial | Target Info | ||
| UniProt ID | TNR6_HUMAN | ||||
| Gene Name | FAS | ||||
| Gene ID | 355 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Stress-activated protein kinase JNK1 (JNK1) | Target Info | PPI Info | [1] | |
| Apoptosis mediating surface antigen FAS (FAS) | Target Info | PPI Info | [2] | ||
| Interacting Patented-recorded Target(s) | Caspase-8 (CASP8) | Target Info | PPI Info | [3] | |
| Caspase-10 (CASP10) | Target Info | PPI Info | [4] | ||
| Interacting Discontinued Target(s) | Transforming protein RhoA (RHOA) | Target Info | PPI Info | [1] | |
| Interacting Literature-reported Target(s) | Apoptosis antigen ligand (CD178) | Target Info | PPI Info | [5] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy. J Biol Chem. 2005 Mar 25;280(12):11641-7. | ||||
| REF 2 | Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis. Free Radic Biol Med. 2011 May 15;50(10):1252-62. | ||||
| REF 3 | Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 1997 Jun;6(6):751-63. | ||||
| REF 4 | Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J Biol Chem. 1997 Mar 7;272(10):6578-83. | ||||
| REF 5 | Identification of amino acid residues important for ligand binding to Fas. J Exp Med. 1997 Apr 21;185(8):1487-92. | ||||
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