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Protein General Information |
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Full Name |
Structural maintenance of chromosomes protein 1A (SMC1A)
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UniProt ID |
SMC1A_HUMAN
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Gene Name |
SMC1A
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Gene ID |
8243
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
ATM serine/threonine kinase (ATM) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
DNA replication licensing factor MCM6 (MCM6) |
Target Info
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PPI Info
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[2] |
DNA replication licensing factor MCM7 (MCM7) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev. 2002 Mar 1;16(5):560-70.
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REF 2 |
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun. 2016 May 13;7:11491.
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REF 3 |
Direct interaction between cohesin complex and DNA replication machinery. Biochem Biophys Res Commun. 2006 Mar 17;341(3):770-5.
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