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Protein General Information |
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Full Name |
E3 ubiquitin-protein ligase NRDP1 (RNF41)
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UniProt ID |
RNF41_HUMAN
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Gene Name |
RNF41
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Gene ID |
10193
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Interacting TTD Target Information |
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Interacting Preclinical Target(s) |
Ubiquitin isopeptidase Y (USP8) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
Suppressor of G2 allele of SKP1 homolog (Sgt1) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem. 2006 Dec 8;281(49):38061-70.
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REF 2 |
Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1. J Biol Chem. 2017 Aug 25;292(34):13947-13958.
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