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| Protein General Information |
Top |
| Full Name |
Serine/threonine-protein kinase PAK 6 (PAK6)
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| UniProt ID |
PAK6_HUMAN
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| Gene Name |
PAK6
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| Gene ID |
56924
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Androgen receptor (AR) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Ubiquitin-protein ligase E3 Mdm2 (MDM2) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. J Biol Chem. 2001 May 4;276(18):15345-53.
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| REF 2 |
p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2). J Biol Chem. 2013 Feb 1;288(5):3359-69.
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