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Protein General Information |
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Full Name |
Histone-lysine N-methyltransferase NSD3 (NSD3)
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UniProt ID |
NSD3_HUMAN
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Gene Name |
WHSC1L1
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Gene ID |
54904
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
Bromodomain-containing protein 4 (BRD4) |
Target Info
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PPI Info
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[1] |
Interacting Patented-recorded Target(s) |
Lysine-specific histone demethylase 1B (KDM1B) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Mol Cell Biol. 2011 Jul;31(13):2641-52.
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REF 2 |
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell. 2010 Jul 30;39(2):222-33.
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