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| Protein General Information |
Top |
| Full Name |
Menin (MEN1)
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| UniProt ID |
MEN1_HUMAN
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| Gene Name |
MEN1
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| Gene ID |
4221
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| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
DNA-binding factor KBF1 (p105) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Mixed-lineage leukemia protein (MLL) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. Oncogene. 2001 Aug 16;20(36):4917-25.
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| REF 2 |
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol. 2004 Jul;24(13):5639-49.
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