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Protein General Information (TTD Target) |
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Full Name |
Ribosomal protein S6 kinase alpha-1 (RSK1)
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Patented-recorded
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Target Info
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UniProt ID |
KS6A1_HUMAN
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Gene Name |
RPS6KA1
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Gene ID |
6195
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Fibroblast growth factor receptor 1 (FGFR1) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Extracellular signal-regulated kinase 2 (ERK2) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. J Biol Chem. 2004 Jul 9;279(28):29325-35.
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REF 2 |
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell. 2005 Jul 22;19(2):159-70.
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