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| Protein General Information |
Top |
| Full Name |
Inhibitor of growth protein 4 (ING4)
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| UniProt ID |
ING4_HUMAN
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| Gene Name |
ING4
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| Gene ID |
51147
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Cellular tumor antigen p53 (TP53) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
HIF-prolyl hydroxylase 2 (HPH-2) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. Cancer Res. 2003 May 15;63(10):2373-8.
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| REF 2 |
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis. Blood. 2007 Dec 15;110(13):4464-75.
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