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| Protein General Information |
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| Full Name |
Fanconi anemia group D2 protein (FANCD2)
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| UniProt ID |
FACD2_HUMAN
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| Gene Name |
FANCD2
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| Gene ID |
2177
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Serine/threonine-protein kinase ATR (FRP1) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Deubiquitinating enzyme 1 (USP1) |
Target Info
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PPI Info
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[2] |
| Breast cancer type 2 susceptibility protein (BRCA2) |
Target Info
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PPI Info
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[3] |
| References |
Top |
| REF 1 |
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol. 2006 Sep;26(18):7005-15.
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| REF 2 |
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell. 2005 Feb 4;17(3):331-9.
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| REF 3 |
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum Mol Genet. 2004 Jun 15;13(12):1241-8.
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