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| Protein General Information (TTD Target) |
Top |
| Full Name |
Ephrin type-B receptor 2 (EPHB2)
|
Clinical trial
|
Target Info
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| UniProt ID |
EPHB2_HUMAN
|
| Gene Name |
EPHB2
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| Gene ID |
2048
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Proto-oncogene c-Src (SRC) |
Target Info
|
PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Ephrin type-B receptor 2 (EPHB2) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region. Oncogene. 1998 May;16(20):2657-70.
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| REF 2 |
Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer. Br J Cancer. 2008 Oct 7;99(7):1074-82.
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