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| Protein General Information |
Top |
| Full Name |
Elongin-B (ELOB)
|
| UniProt ID |
ELOB_HUMAN
|
| Gene Name |
TCEB2
|
| Gene ID |
6923
|
| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
Hypoxia-inducible factor 1 alpha (HIF-1A) |
Target Info
|
PPI Info
|
[1] |
| Tumor expressed melanoma antigen (PRAME) |
Target Info
|
PPI Info
|
[3] |
| Interacting Patented-recorded Target(s) |
von Hippel-Lindau disease tumor suppressor (VHL) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
NEDD8 acts as a 'molecular switch' defining the functional selectivity of VHL. EMBO Rep. 2008 May;9(5):486-91.
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| REF 2 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 3 |
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. EMBO J. 2011 Aug 5;30(18):3786-98.
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