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| Protein General Information |
Top |
| Full Name |
Denticleless protein homolog (DTL)
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| UniProt ID |
DTL_HUMAN
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| Gene Name |
DTL
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| Gene ID |
51514
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Proliferating cell nuclear antigen (PCNA) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
JUN activation domain binding protein (COPS5) |
Target Info
|
PPI Info
|
[2] |
| Melanoma differentiation-associated protein 6 (CDKN1A) |
Target Info
|
PPI Info
|
[3] |
| References |
Top |
| REF 1 |
L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage. Cell Cycle. 2006 Aug;5(15):1675-80.
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| REF 2 |
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell. 2010 Dec 10;143(6):951-65.
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| REF 3 |
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev. 2008 Sep 15;22(18):2496-506.
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