Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Direct IAP-binding protein with low pI (DIABLO) | Literature-reported | Target Info | ||
| UniProt ID | DBLOH_HUMAN | ||||
| Gene Name | DIABLO | ||||
| Gene ID | 56616 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Apoptosis inhibitor survivin (BIRC5) | Target Info | PPI Info | [1] | |
| Cellular inhibitor of apoptosis 1 (BIRC2) | Target Info | PPI Info | [2] | ||
| Cellular inhibitor of apoptosis 2 (BIRC3) | Target Info | PPI Info | [3] | ||
| X-linked inhibitor of apoptosis protein (XIAP) | Target Info | PPI Info | [4] | ||
| Interacting Patented-recorded Target(s) | Melanoma inhibitor of apoptosis protein (ML-IAP) | Target Info | PPI Info | [5] | |
| Interacting Literature-reported Target(s) | Direct IAP-binding protein with low pI (DIABLO) | Target Info | PPI Info | [6] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Survivin monomer plays an essential role in apoptosis regulation. J Biol Chem. 2011 Jul 1;286(26):23296-307. | ||||
| REF 2 | The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein. J Biol Chem. 2003 Oct 3;278(40):38699-706. | ||||
| REF 3 | The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation. J Biol Chem. 2014 Sep 12;289(37):25721-36. | ||||
| REF 4 | Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 2000 Dec 21-28;408(6815):1004-8. | ||||
| REF 5 | Livin modulates the apoptotic effects of vesicular stomatotitis virus in lung adenocarcinoma. Int J Oncol. 2015 Nov;47(5):1775-82. | ||||
| REF 6 | Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature. 2000 Aug 24;406(6798):855-62. | ||||
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