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| Protein General Information (TTD Target) |
Top |
| Full Name |
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
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Literature-reported
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Target Info
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| UniProt ID |
4EBP1_HUMAN
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| Gene Name |
EIF4EBP1
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| Gene ID |
1978
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Serine/threonine-protein kinase mTOR (mTOR) |
Target Info
|
PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
ATM serine/threonine kinase (ATM) |
Target Info
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PPI Info
|
[2] |
| Interacting Literature-reported Target(s) |
Eukaryotic initiation factor 4E (EIF4E) |
Target Info
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PPI Info
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[3] |
| References |
Top |
| REF 1 |
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38. Science. 2007 Nov 9;318(5852):977-80.
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| REF 2 |
Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase. J Biol Chem. 2000 Mar 17;275(11):7803-10.
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| REF 3 |
Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase. J Biol Chem. 2000 Apr 14;275(15):10779-87.
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