Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T11791 Target Info
Target Name Acetyl-CoA transporter (SLC33A1)
Synonyms Solute carrier family 33 member 1; Acetyl-coenzyme A transporter 1; Acetyl-CoA transporter 1; AT1 protein; AT-1; ACATN
Target Type Patented-recorded Target
Gene Name SLC33A1
Biochemical Class Major facilitator
UniProt ID
ACATN_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US8592431
Title Fused ring compound and use thereof
Abstract Provided is a novel compound represented by the following formula Wherein each symbol is as defined in the specification, or a salt thereof, which has an angiotensin II receptor antagonistic activity and a peroxisome proliferator-activated receptor agonistic activity, and is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and/or metabolic diseases such as diabetes and the like, and the like.
Applicant(s) Takeda Pharmaceutical Company Limited
Representative Drug(s) D0K8EF Drug Info IC50 = 1.8 nM Click to Show More [1]
2 D0Z5GO Drug Info IC50 = 2.3 nM [1]
3 D0TI5Y Drug Info IC50 = 3.2 nM [1]
Patent ID US8592431
Title Fused ring compound and use thereof
Abstract Provided is a novel compound represented by the following formula Wherein each symbol is as defined in the specification, or a salt thereof, which has an angiotensin II receptor antagonistic activity and a peroxisome proliferator-activated receptor agonistic activity, and is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and/or metabolic diseases such as diabetes and the like, and the like.
Applicant(s) Takeda Pharmaceutical Company Limited
Representative Drug(s) D0K8EF Drug Info IC50 = 1.8 nM Click to Show More [1]
2 D0Z5GO Drug Info IC50 = 2.3 nM [1]
3 D0TI5Y Drug Info IC50 = 3.2 nM [1]
Patent ID US8592431
Title Fused ring compound and use thereof
Abstract Provided is a novel compound represented by the following formula Wherein each symbol is as defined in the specification, or a salt thereof, which has an angiotensin II receptor antagonistic activity and a peroxisome proliferator-activated receptor agonistic activity, and is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and/or metabolic diseases such as diabetes and the like, and the like.
Applicant(s) Takeda Pharmaceutical Company Limited
Representative Drug(s) D0K8EF Drug Info IC50 = 1.8 nM Click to Show More [1]
2 D0Z5GO Drug Info IC50 = 2.3 nM [1]
3 D0TI5Y Drug Info IC50 = 3.2 nM [1]
References  Top
REF 1 Fused ring compound and use thereof. US8592431.

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