miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-744-5p | ||||
miRNA Stemloop AC | MI0005559 | ||||
miRNA Stemloop ID | hsa-mir-744 | ||||
Sequence | ugcggggcuagggcuaacagca | ||||
TTD Target(s) Regulated by This miRNA | Glycogen synthase kinase-3 beta (GSK-3B) | Clinical trial Target | Target Info | [1] | |
Proto-oncogene c-Myc (MYC) | Literature-reported Target | Target Info | [2] | ||
Protein(s) Regulated by This miRNA | Elongation factor 1-alpha 2 | Regulated Protein | [3] | ||
Protein naked cuticle homolog 1 | Regulated Protein | [1] | |||
Rho GTPase-activating protein 5 | Regulated Protein | [5] | |||
Secreted frizzled-related protein 1 | Regulated Protein | [1] | |||
Transducin-like enhancer protein 3 | Regulated Protein | [1] | |||
References | |||||
REF 1 | MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/-catenin signaling. Oncotarget. 2017 Feb 28;8(9):14693-14707. | ||||
REF 2 | Decrease expression of microRNA-744 promotes cell proliferation by targeting c-Myc in human hepatocellular carcinoma. Cancer Cell Int. 2014 Jun 22;14:58. | ||||
REF 3 | Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744.Br J Cancer. 2013 Jun 11;108(11):2304-11. | ||||
REF 4 | MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/-catenin signaling. Oncotarget. 2017 Feb 28;8(9):14693-14707. | ||||
REF 5 | MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5.Oncotarget. 2015 May 30;6(15):13164-75. |
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