miRNA General Information
miRNA Mature ID hsa-miR-455-5p
miRNA Stemloop AC MI0003513
miRNA Stemloop ID hsa-mir-455
Sequence uaugugccuuuggacuacaucg
TTD Target(s) Regulated by This miRNA Ribosomal protein S6 kinase beta-1 (S6K1) Clinical trial Target Target Info [1]
Suppressor of cytokine signaling 3 (SOCS3) Literature-reported Target Target Info [2]
Protein(s) Regulated by This miRNA Nicastrin Regulated Protein [3]
Ras-related protein Rab-18 Regulated Protein [4]
Ubiquitin-like modifier-activating enzyme 7 Regulated Protein [5]
References
REF 1 TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network. Genome Res. 2016 Mar;26(3):331-41.
REF 2 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. Mol Med Rep. 2017 Apr;15(4):2143-2153.
REF 3 MicroRNAs targeting Nicastrin regulate A production and are affected by target site polymorphisms.Front Mol Neurosci. 2014 Jul 18;7:67.
REF 4 MiR-455-5p acts as a novel tumor suppressor in gastric cancer by down-regulating RAB18.Gene. 2016 Nov 5;592(2):308-15.
REF 5 Up-regulation of miR-455-5p by the TGF--SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B.J Pathol. 2016 Sep;240(1):38-49.

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