miRNA General Information
miRNA Mature ID hsa-miR-410-3p
miRNA Stemloop AC MI0002465
miRNA Stemloop ID hsa-mir-410
Sequence aauauaacacagauggccugu
TTD Target(s) Regulated by This miRNA Angiotensin II receptor type-1 (AGTR1) Successful Target Target Info [1]
Proto-oncogene c-Met (MET) Successful Target Target Info [2]
Ubiquitin-protein ligase E3 Mdm2 (MDM2) Clinical trial Target Target Info [3]
Notch-1 receptor (NOTCH1) Clinical trial Target Target Info [4]
G2/mitotic-specific cyclin B1 (CCNB1) Patented-recorded Target Target Info [5]
Jagged-2 protein (JAG2) Literature-reported Target Target Info [4]
Protein(s) Regulated by This miRNA Hairy/enhancer-of-split related with YRPW motif protein 1 Regulated Protein [4]
Protein jagged-1 Regulated Protein [4]
Transcription factor HES-1 Regulated Protein [4]
Zinc finger protein SNAI1 Regulated Protein [7]
References
REF 1 MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer. IUBMB Life. 2015 Jan;67(1):42-53.
REF 2 MiR-410 regulates MET to influence the proliferation and invasion of glioma. Int J Biochem Cell Biol. 2012 Nov;44(11):1711-7.
REF 3 MicroRNA-410 suppresses migration and invasion by targeting MDM2 in gastric cancer. PLoS One. 2014 Aug 19;9(8):e104510.
REF 4 Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34(1):302-10.
REF 5 Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors. Cell Cycle. 2015;14(16):2590-7.
REF 6 Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34(1):302-10.
REF 7 miR-410-3p suppresses breast cancer progression by targeting Snail.Oncol Rep. 2016 Jul;36(1):480-6.

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