miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-367-3p | ||||
miRNA Stemloop AC | MI0000775 | ||||
miRNA Stemloop ID | hsa-mir-367 | ||||
Sequence | aauugcacuuuagcaaugguga | ||||
TTD Target(s) Regulated by This miRNA | Ubiquitin-protein ligase E3 Mdm2 (MDM2) | Clinical trial Target | Target Info | [1] | |
Kruppel like factor 4 (KLF4) | Clinical trial Target | Target Info | [2] | ||
F-box and WD-40 domain protein 7 (Fbxw7) | Literature-reported Target | Target Info | [3] | ||
Protein(s) Regulated by This miRNA | Ras-related protein Rab-23 | Regulated Protein | [4] | ||
References | |||||
REF 1 | The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals. EBioMedicine. 2016 Oct;12:55-67. | ||||
REF 2 | MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 2009 May 15;137(4):647-58. | ||||
REF 3 | miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7. Oncol Rep. 2017 Feb;37(2):1052-1058. | ||||
REF 4 | The microRNA-367 inhibits the invasion and metastasis of gastric cancer by directly repressing Rab23.Genet Test Mol Biomarkers. 2015 Feb;19(2):69-74. |
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