miRNA General Information
miRNA Mature ID hsa-miR-342-3p
miRNA Stemloop AC MI0000805
miRNA Stemloop ID hsa-mir-342
Sequence ucucacacagaaaucgcacccgu
TTD Target(s) Regulated by This miRNA DNA [cytosine-5]-methyltransferase 1 (DNMT1) Clinical trial Target Target Info [1]
E2F transcription factor 1 (E2F1) Clinical trial Target Target Info [2]
Metastasis adhesion protein (MTDH) Literature-reported Target Target Info [3]
Sterol regulatory element binding protein-1 (SREBF1) Literature-reported Target Target Info [4]
T-lymphoma invasion and metastasis 1 (TIAM1) Literature-reported Target Target Info [5]
Protein(s) Regulated by This miRNA Ankyrin repeat domain-containing protein 49 Regulated Protein [6]
Baculoviral IAP repeat-containing protein 6 Regulated Protein [7]
Bone morphogenetic protein 7 Regulated Protein [8]
C-terminal-binding protein 2 Regulated Protein [9]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 Regulated Protein [5]
Cytoplasmic polyadenylation element-binding protein 4 Regulated Protein [5]
DNA-binding protein inhibitor ID-4 Regulated Protein [11]
E3 ubiquitin-protein transferase RMND5A Regulated Protein [5]
Gem-associated protein 4 Regulated Protein [8]
Glucose-induced degradation protein 8 homolog Regulated Protein [5]
NF-kappa-B essential modulator Regulated Protein [12]
Sterol regulatory element-binding protein 2 Regulated Protein [4]
Synaptopodin 2-like protein Regulated Protein [5]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Regulated Protein [12]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 Regulated Protein [12]
References
REF 1 MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. Carcinogenesis. 2011 Jul;32(7):1033-42.
REF 2 miR-342-3p regulates MYC transcriptional activity via direct repression of E2F1 in human lung cancer. Carcinogenesis. 2015 Dec;36(12):1464-73.
REF 3 Long noncoding RNA FTX is upregulated in gliomas and promotes proliferation and invasion of glioma cells by negatively regulating miR-342-3p. Lab Invest. 2017 Apr;97(4):447-457.
REF 4 MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. PLoS One. 2013 Aug 9;8(8):e70987.
REF 5 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets. PLoS One. 2012;7(7):e40676.
REF 6 MicroRNA profiling in chemoresistant and chemosensitive acute myeloid leukemia.Cytogenet Genome Res. 2013;141(4):272-6.
REF 7 miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells.Oncotarget. 2016 Apr 5;7(14):18594-604.
REF 8 Downregulation of miR-342 is associated with tamoxifen resistant breast tumors.Mol Cancer. 2010 Dec 20;9:317.
REF 9 Obesity-Associated MiR-342-3p Promotes Adipogenesis of Mesenchymal Stem Cells by Suppressing CtBP2 and Releasing C/EBP from CtBP2 Binding.Cell Physiol Biochem. 2015;35(6):2285-98.
REF 10 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets. PLoS One. 2012;7(7):e40676.
REF 11 miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer.PLoS One. 2014 Jan 27;9(1):e87039.
REF 12 miR-342-3p affects hepatocellular carcinoma cell proliferation via regulating NF-B pathway.Biochem Biophys Res Commun. 2015 Feb 13;457(3):370-7.
REF 13 MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. PLoS One. 2013 Aug 9;8(8):e70987.

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