miRNA General Information
miRNA Mature ID hsa-miR-328-3p
miRNA Stemloop AC MI0000804
miRNA Stemloop ID hsa-mir-328
Sequence cuggcccucucugcccuuccgu
TTD Target(s) Regulated by This miRNA ATP-binding cassette transporter G2 (ABCG2) Successful Target Target Info [1]
Voltage-gated potassium channel Kv11.1 (KCNH2) Successful Target Target Info [2]
Beta-secretase 1 (BACE1) Clinical trial Target Target Info [3]
Extracellular matrix receptor III (CD44) Clinical trial Target Target Info [4]
FK506-binding protein 4 (FKBP4) Literature-reported Target Target Info [5]
Matrix metalloproteinase-16 (MMP-16) Literature-reported Target Target Info [6]
Protein-tyrosine phosphatase eta (HPTP) Patented-recorded Target Target Info [7]
Gamma-Histone H2AX (H2AFX) Literature-reported Target Target Info [8]
Protein(s) Regulated by This miRNA 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 Regulated Protein [9]
Secreted frizzled-related protein 1 Regulated Protein [10]
References
REF 1 MicroRNAs play a role in the development of human hematopoietic stem cells. J Cell Biochem. 2008 Jun 1;104(3):805-17.
REF 2 Arsenic trioxide inhibits breast cancer cell growth via microRNA-328/hERG pathway in MCF-7 cells. Mol Med Rep. 2015 Jul;12(1):1233-8.
REF 3 MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J. 2008 Dec;22(12):4126-35.
REF 4 The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol. 2008 Feb;10(2):202-10.
REF 5 Transcriptomic profiling of platelet senescence and platelet extracellular vesicles. Transfusion. 2017 Jan;57(1):144-156.
REF 6 MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer. Br J Cancer. 2012 Mar 27;106(7):1320-30.
REF 7 Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328. FEBS J. 2013 Jan;280(2):401-12.
REF 8 miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat Struct Mol Biol. 2009 May;16(5):492-8.
REF 9 MiR-328 suppresses the survival of esophageal cancer cells by targeting PLCE1.Biochem Biophys Res Commun. 2016 Jan 29;470(1):175-180.
REF 10 MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation.Neuro Oncol. 2014 Jan;16(2):179-90.

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