miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-32-5p | ||||
miRNA Stemloop AC | MI0000090 | ||||
miRNA Stemloop ID | hsa-mir-32 | ||||
Sequence | uauugcacauuacuaaguugca | ||||
TTD Target(s) Regulated by This miRNA | Aurora kinase A (AURKA) | Clinical trial Target | Target Info | [1] | |
Ubiquitin-protein ligase E3 Mdm2 (MDM2) | Clinical trial Target | Target Info | [2] | ||
Protein arginine methyltransferase 5 (PRMT5) | Clinical trial Target | Target Info | [3] | ||
Kruppel like factor 4 (KLF4) | Clinical trial Target | Target Info | [4] | ||
Histone acetyltransferase KAT2B (KAT2B) | Literature-reported Target | Target Info | [5] | ||
Phosphatase and tensin homolog (PTEN) | Literature-reported Target | Target Info | [6] | ||
F-box and WD-40 domain protein 7 (Fbxw7) | Literature-reported Target | Target Info | [7] | ||
Protein(s) Regulated by This miRNA | Bcl-2-like protein 11 | Regulated Protein | [8] | ||
DNA polymerase zeta catalytic subunit | Regulated Protein | [9] | |||
Hamartin | Regulated Protein | [2] | |||
PH domain leucine-rich repeat-containing protein phosphatase 2 | Regulated Protein | [11] | |||
Protein BTG2 | Regulated Protein | [12] | |||
Regulator of G-protein signaling 17 | Regulated Protein | [13] | |||
Solute carrier family 45 member 3 | Regulated Protein | [14] | |||
TNF receptor-associated factor 3 | Regulated Protein | [15] | |||
Twist-related protein 1 | Regulated Protein | [16] | |||
References | |||||
REF 1 | A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins. Nat Methods. 2011 May 15;8(7):559-64. | ||||
REF 2 | MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5316-21. | ||||
REF 3 | Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells. Mol Cell Biol. 2008 Oct;28(20):6262-77. | ||||
REF 4 | MiR-32 promotes gastric carcinoma tumorigenesis by targeting Kruppel-like factor 4. Biochem Biophys Res Commun. 2015 Nov 27;467(4):913-20. | ||||
REF 5 | MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12885-90. | ||||
REF 6 | Downregulated microRNA-32 expression induced by high glucose inhibits cell cycle progression via PTEN upregulation and Akt inactivation in bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun. 2013 Apr 19;433(4):526-31. | ||||
REF 7 | MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7. Cancer Cell Int. 2017 Jan 25;17:14. | ||||
REF 8 | Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res. 2008 Aug 1;68(15):6162-70. | ||||
REF 9 | REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility.Oncogene. 2013 Jan 10;32(2):242-50. | ||||
REF 10 | MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5316-21. | ||||
REF 11 | MiR-32 contributed to cell proliferation of human breast cancer cells by suppressing of PHLPP2 expression.Biomed Pharmacother. 2015 Oct;75:105-10. | ||||
REF 12 | SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes.Nat Commun. 2015 Sep 23;6:8257. | ||||
REF 13 | Deregulation of RGS17 Expression Promotes Breast Cancer Progression.J Cancer. 2015 Jul 3;6(8):767-75. | ||||
REF 14 | miR-32 and its target SLC45A3 regulate the lipid metabolism of oligodendrocytes and myelin.Neuroscience. 2012 Jun 28;213:29-37. | ||||
REF 15 | HIV-1 Tat C-mediated regulation of tumor necrosis factor receptor-associated factor-3 by microRNA 32 in human microglia.J Neuroinflammation. 2012 Jun 18;9:131. | ||||
REF 16 | miR-32 inhibits proliferation, epithelial-mesenchymal transition, and metastasis by targeting TWIST1 in non-small-cell lung cancer cells.Onco Targets Ther. 2016 Mar 14;9:1489-98. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.