miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-29a-5p | ||||
miRNA Stemloop AC | MI0000087 | ||||
miRNA Stemloop ID | hsa-mir-29a | ||||
Sequence | acugauuucuuuugguguucag | ||||
TTD Target(s) Regulated by This miRNA | Glycogen synthase kinase-3 beta (GSK-3B) | Clinical trial Target | Target Info | [1] | |
Dickkopf-related protein 1 (DKK1) | Clinical trial Target | Target Info | [1] | ||
Histone deacetylase 9 (HDAC9) | Patented-recorded Target | Target Info | [2] | ||
Phosphatase and tensin homolog (PTEN) | Literature-reported Target | Target Info | [3] | ||
Osteonectin (SPARC) | Literature-reported Target | Target Info | [4] | ||
Protein(s) Regulated by This miRNA | Bile salt sulfotransferase | Regulated Protein | [5] | ||
Collagen alpha-1(III) chain | Regulated Protein | [4] | |||
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Regulated Protein | [7] | |||
References | |||||
REF 1 | miR-29a modulates tumor necrosis factor--induced osteogenic inhibition by targeting Wnt antagonists. Dev Growth Differ. 2015 Apr;57(3):264-73. | ||||
REF 2 | TGF-1 Reduces miR-29a Expression to Promote Tumorigenicity and Metastasis of Cholangiocarcinoma by Targeting HDAC4. PLoS One. 2015 Oct 6;10(10):e0136703. | ||||
REF 3 | MiR-29a Regulates Radiosensitivity in Human Intestinal Cells by Targeting PTEN Gene. Radiat Res. 2016 Sep;186(3):292-301. | ||||
REF 4 | miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression. PLoS One. 2015 Mar 18;10(3):e0120969. | ||||
REF 5 | MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease.Nat Commun. 2015 Apr 10;6:6774. | ||||
REF 6 | miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression. PLoS One. 2015 Mar 18;10(3):e0120969. | ||||
REF 7 | MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF- activated kinase 1 binding protein 1, implications for systemic sclerosis.PLoS One. 2014 Dec 30;9(12):e115596. |
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