miRNA General Information
miRNA Mature ID hsa-miR-150-3p
miRNA Stemloop AC MI0000479
miRNA Stemloop ID hsa-mir-150
Sequence cugguacaggccugggggacag
TTD Target(s) Regulated by This miRNA Insulin-like growth factor I receptor (IGF1R) Successful Target Target Info [1]
Beta-catenin (CTNNB1) Successful Target Target Info [2]
Cellular tumor antigen p53 (TP53) Clinical trial Target Target Info [3]
Protein(s) Regulated by This miRNA 60S ribosomal protein L11 Regulated Protein [4]
C-C chemokine receptor type 6 Regulated Protein [5]
References
REF 1 Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R. PLoS One. 2013 May 10;8(5):e61015.
REF 2 TNF--induced NF-B activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting -catenin. Open Biol. 2016 Mar;6(3). pii: 150258.
REF 3 Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth. PLoS One. 2016 Apr 15;11(4):e0153689.
REF 4 Down-regulation of 5S rRNA by miR-150 and miR-383 enhances c-Myc-rpL11 interaction and inhibits proliferation of esophageal squamous carcinoma cells.FEBS Lett. 2015 Dec 21;589(24 Pt B):3989-97.
REF 5 Histone deacetylase inhibitors inhibit metastasis by restoring a tumor suppressive microRNA-150 in advanced cutaneous T-cell lymphoma.Oncotarget. 2017 Jan 31;8(5):7572-7585.

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