Drug Information
Drug General Information | Top | |||
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Drug ID |
D0ZQ3Q
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Former ID |
DNC013659
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Drug Name |
1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine
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Synonyms |
2,5-Dimethoxy-4-ethylamphetamine; 1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine; 22004-32-6; DOET; CHEMBL8224; NCGC00247691-01; SCHEMBL1740704; DOET,(-); AC1L1D54; CTK4E8216; BDBM81965; HXJKWPGVENNMCC-UHFFFAOYSA-N; 4-Ethyl-2,5-dimethoxyamphetamine; PDSP2_000785; CAS_62066; PDSP1_001371; PDSP2_001355; PDSP1_000797; NSC_62066; DB01467; ACM22004326; 2,5-dimethoxy-4-ethylamphetamine (''DOEt''); L001150; Benzeneethanamine,4-ethyl-2,5-dimethoxy-a-methyl-; 1-(4-Ethyl-2,5-dimethoxyphenyl)-2-propanamine #; Phenethylamine, 4-ethyl-2,5-dimeth
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C13H21NO2
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Canonical SMILES |
CCC1=CC(=C(C=C1OC)CC(C)N)OC
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InChI |
1S/C13H21NO2/c1-5-10-7-13(16-4)11(6-9(2)14)8-12(10)15-3/h7-9H,5-6,14H2,1-4H3
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InChIKey |
HXJKWPGVENNMCC-UHFFFAOYSA-N
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CAS Number |
CAS 22004-32-6
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. |
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