Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0Z7LS
|
|||
Former ID |
DNC010137
|
|||
Drug Name |
3,3-Diethyl-1-o-tolylazetidine-2,4-dione
|
|||
Synonyms |
CHEMBL566918; 3,3-Diethyl-1-o-tolylazetidine-2,4-dione
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C14H17NO2
|
|||
Canonical SMILES |
CCC1(C(=O)N(C1=O)C2=CC=CC=C2C)CC
|
|||
InChI |
1S/C14H17NO2/c1-4-14(5-2)12(16)15(13(14)17)11-9-7-6-8-10(11)3/h6-9H,4-5H2,1-3H3
|
|||
InChIKey |
QNAKQLGCEYBHNC-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Neutrophil elastase (NE) | Target Info | Inhibitor | [1] |
KEGG Pathway | Transcriptional misregulation in cancer | |||
Systemic lupus erythematosus | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
C-MYB transcription factor network | ||||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||
Human Complement System | ||||
Degradation of collagen |
References | Top | |||
---|---|---|---|---|
REF 1 | 4-Oxo-beta-lactams (azetidine-2,4-diones) are potent and selective inhibitors of human leukocyte elastase. J Med Chem. 2010 Jan 14;53(1):241-53. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.