Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z4SW
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| Drug Name |
Benzimidazole derivative 8
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| Synonyms |
PMID26936077-Compound-25
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| Drug Type |
Small molecular drug
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| Company |
NEOPHARM CO.,LTD. ( ) GWAK, Hyung Sub KIM, Yong Zu KIM, Uk Il PARK, Byeong Deog PARK, Tae Kyo WOO, Sung Ho
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| Structure |
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Download2D MOL |
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| Formula |
C22H25N3O
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| Canonical SMILES |
CC1=CC(=CC=C1)CN2C(=NC3=C2C=CC(=C3)C(=O)N4CCCCC4)C
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| InChI |
1S/C22H25N3O/c1-16-7-6-8-18(13-16)15-25-17(2)23-20-14-19(9-10-21(20)25)22(26)24-11-4-3-5-12-24/h6-10,13-14H,3-5,11-12,15H2,1-2H3
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| InChIKey |
FWLBCCWBWAZRLY-UHFFFAOYSA-N
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| CAS Number |
CAS 1234208-67-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Proteinase activated receptor 2 (PAR2) | Target Info | Antagonist | [1] |
| Target's Patent Info | Proteinase activated receptor 2 (PAR2) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| African trypanosomiasis | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83. | |||
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