Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Z3DY
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Former ID |
DCL000306
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Drug Name |
Benzbromarone
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Synonyms |
Acifugan; Azubromaron; Benzbromaron; Benzbromaronratiopharm; Benzbromaronum; Benzobromarona; Besuric; Desuric; Exurate; Harolan; Hipurik; Minuric; Narcaricin; Normurat; Uricovac; Urinorm; Uroleap; Aliud Brand of Benzbromarone; Benzbromaron AL; Benzbromaron ratiopharm; Benzbromarone Aliud Brand; Benzbromarone Heumann Brand; Benzbromarone Sanfer Brand; Benzbromarone ratiopharm Brand; Heumann Brand of Benzbromarone; Ratiopharm Brand of Benzbromarone; Sanfer Brand of Benzbromarone; Sanofi Winthrop Brand of Benzbromarone; L 2214; L2214; MJ 10061; NCI85433; AL, Benzbromaron; Benzbromaron-ratiopharm; Benzbromaronum [INN-Latin]; Benzobromarona [INN-Spanish]; L 2214-Labaz; L-2214; Uroleap (TN); Benzbromarone [USAN:INN:BAN]; Methanone, (3; Benzbromarone (JP15/USAN/INN); KETONE, 3,5-DIBROMO-4-HYDROXYPHENYL 2-ETHYL-3-BENZOFURANYL; Ketone, 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl; (2-Ethyl-3-benzofuranyl)-(3,5-dibrom-4-hydroxyphenyl)keton; (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone; (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone; 2-Ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran; 3, 5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone; 3,5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone; 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran; 3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
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Drug Type |
Small molecular drug
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Indication | Gout [ICD-11: FA25; ICD-10: M10] | Approved | [1] | |
Company |
Labaz Laboratories
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Structure |
Download2D MOL |
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Formula |
C17H12Br2O3
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Canonical SMILES |
CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br
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InChI |
1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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InChIKey |
WHQCHUCQKNIQEC-UHFFFAOYSA-N
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CAS Number |
CAS 3562-84-3
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PubChem Compound ID | ||||
PubChem Substance ID |
122758, 221763, 855676, 4253342, 4572619, 7848119, 8139271, 8151561, 10320943, 10321664, 11110651, 11446236, 11458917, 11461081, 11466398, 11467518, 11486156, 11533498, 15329540, 24424558, 24891861, 26653345, 26664708, 29221503, 46386951, 47291274, 47810917, 47959937, 48185143, 48259414, 48415612, 49681786, 49698460, 49988150, 50100155, 50103990, 50804618, 56422114, 57321259, 57653945, 76715662, 85787503, 89471954, 92125465, 92308014, 92308634, 92722452, 99450936, 103513016, 103914152
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ChEBI ID |
CHEBI:3023
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SuperDrug ATC ID |
M04AB03
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Target and Pathway | Top | |||
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Target(s) | Calcium-dependent chloride channel anoctamin (ANO) | Target Info | Antagonist | [2] |
Multidrug resistance-associated protein 1 (ABCC1) | Target Info | Stimulator | [3] | |
KEGG Pathway | ABC transporters | |||
Sphingolipid signaling pathway | ||||
Vitamin digestion and absorption | ||||
MicroRNAs in cancer | ||||
NetPath Pathway | IL6 Signaling Pathway | |||
Pathway Interaction Database | S1P1 pathway | |||
Sphingosine 1-phosphate (S1P) pathway | ||||
Reactome | Cobalamin (Cbl, vitamin B12) transport and metabolism | |||
ABC-family proteins mediated transport | ||||
Stimuli-sensing channels | ||||
WikiPathways | Arachidonic acid metabolism | |||
Irinotecan Pathway | ||||
Metabolism of water-soluble vitamins and cofactors |
References | Top | |||
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REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
REF 2 | Anoctamin Channels in Human Myometrium: A Novel Target for Tocolysis.Reprod Sci. 2018 Nov;25(11):1589-1600. | |||
REF 3 | Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transpo... Drug Metab Dispos. 2009 Jan;37(1):129-36. |
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