Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0YM6B
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| Former ID |
DNC009039
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| Drug Name |
5'-Deoxy-5'-(N,N-dimethylamino)-8-methyladenosine
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| Synonyms |
5'-deoxy-5'-(dimethylamino)-8-methyladenosine; SCHEMBL955366; 5'-Deoxy-5'-(N,N-dimethylamino)-8-methyladenosine; CHEMBL516214; AdoMet substrate analogue, 23a; BDBM28452; BDRUNDKEQQVJJG-QYVSTXNMSA-N; (2R,3R,4S,5R)-2-(6-amino-8-methyl-9H-purin-9-yl)-5-[(dimethylamino)methyl]oxolane-3,4-diol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H20N6O3
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| Canonical SMILES |
CC1=NC2=C(N=CN=C2N1C3C(C(C(O3)CN(C)C)O)O)N
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| InChI |
1S/C13H20N6O3/c1-6-17-8-11(14)15-5-16-12(8)19(6)13-10(21)9(20)7(22-13)4-18(2)3/h5,7,9-10,13,20-21H,4H2,1-3H3,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1
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| InChIKey |
BDRUNDKEQQVJJG-QYVSTXNMSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | S-adenosylmethionine decarboxylase proenzyme (AMD1) | Target Info | Inhibitor | [1] |
| BioCyc | Methionine salvage cycle III | |||
| Spermine biosynthesis | ||||
| Spermidine biosynthesis | ||||
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Arginine and proline metabolism | ||||
| Metabolic pathways | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Pathwhiz Pathway | Spermidine and Spermine Biosynthesis | |||
| Methionine Metabolism | ||||
| WikiPathways | Metabolism of amino acids and derivatives | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues ... J Med Chem. 2009 Mar 12;52(5):1388-407. | |||
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