Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y8AN
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| Former ID |
DNC000534
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| Drug Name |
Deprenyl
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| Synonyms |
2323-36-6; CHEBI:50217; N,alpha-Dimethyl-N-2-propynylphenethylamine; N,alpha-Dimethyl-N-2-propynylbenzeneethanamine; methyl(1-phenylpropan-2-yl)(prop-2-yn-1-yl)amine; PHENETHYLAMINE, N,alpha-DIMETHYL-N-2-PROPYNYL-; N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine; dl-Deprenyl; phenylisopropyl-n-methylpropinylamine; AC1L1JT6; CHEMBL8663; SCHEMBL74753; cid_92913; 4-fluorodeprenyl, (-)-isomer; BDBM39862; MEZLKOACVSPNER-UHFFFAOYSA-N; HMS2089B08; AC1Q2862; MCULE-3188554308; ACM2323366
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H17N
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| Canonical SMILES |
CC(CC1=CC=CC=C1)N(C)CC#C
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| InChI |
1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3
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| InChIKey |
MEZLKOACVSPNER-UHFFFAOYSA-N
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| CAS Number |
CAS 2323-36-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7847850, 8169368, 10321789, 12014185, 14822768, 15121497, 24278577, 26719766, 29293585, 46386796, 49681709, 49880109, 56463000, 57310318, 79849348, 81092850, 85273785, 92125589, 92716947, 103770887, 103914274, 104170103, 104298199, 109714021, 119525024, 119526887, 124658795, 124757527, 125164331, 126584522, 126622589, 134339938, 134340702, 134989155, 144204123, 144212163, 162037735, 163414194, 164786719, 170464993, 172080146, 172080728, 175267279, 179149238, 185979595, 187072590, 198970974, 210275063, 210280701, 226426428
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| ChEBI ID |
CHEBI:50217
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation via tryptamine | ||||
| Dopamine degradation | ||||
| Putrescine degradation III | ||||
| Noradrenaline and adrenaline degradation | ||||
| KEGG Pathway | Glycine, serine and threonine metabolism | |||
| Arginine and proline metabolism | ||||
| Histidine metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Tryptophan metabolism | ||||
| Drug metabolism - cytochrome P450 | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Dopaminergic synapse | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5-Hydroxytryptamine degredation | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| WikiPathways | Tryptophan metabolism | |||
| Dopamine metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The effect of deprenyl washout in patients with long-standing Parkinson's disease. J Neural Transm. 2002 May;109(5-6):797-803. | |||
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