Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y5UF
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Former ID |
DNC006294
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Drug Name |
5-bromo-6-(cyclopropylamino)uracil hydrochloride
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Synonyms |
CHEMBL537864
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C7H9BrClN3O2
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Canonical SMILES |
C1CC1NC2=C(C(=O)NC(=O)N2)Br.Cl
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InChI |
1S/C7H8BrN3O2.ClH/c8-4-5(9-3-1-2-3)10-7(13)11-6(4)12;/h3H,1-2H2,(H3,9,10,11,12,13);1H
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InChIKey |
CUQFSKAHEOAMRH-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Thymidine phosphorylase (TYMP) | Target Info | Inhibitor | [1] |
BioCyc | Pyrimidine deoxyribonucleosides degradation | |||
KEGG Pathway | Pyrimidine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Bladder cancer | ||||
NetPath Pathway | TSH Signaling Pathway | |||
Pathwhiz Pathway | Pyrimidine Metabolism | |||
WikiPathways | Bladder Cancer | |||
Metabolism of nucleotides | ||||
Fluoropyrimidine Activity |
References | Top | |||
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REF 1 | Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1335-7. |
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