Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XX9N
|
|||
| Drug Name |
Tetra-hydro-oxazolopyridine derivative 6
|
|||
| Synonyms |
PMID28067079-Compound-66
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
DAINIPPON SUMITOMO PHARMA CO., LTD
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H15ClFN3O2
|
|||
| Canonical SMILES |
CC1=CC(=CC(=C1)Cl)C(=O)N2CCC3=C(C2)N=C(O3)C4=NC=C(C=C4)F
|
|||
| InChI |
1S/C19H15ClFN3O2/c1-11-6-12(8-13(20)7-11)19(25)24-5-4-17-16(10-24)23-18(26-17)15-3-2-14(21)9-22-15/h2-3,6-9H,4-5,10H2,1H3
|
|||
| InChIKey |
NMKCKZQPMUTSIC-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Metabotropic glutamate receptor 5 (mGluR5) | Target Info | Modulator | [1] |
| Target's Patent Info | Metabotropic glutamate receptor 5 (mGluR5) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Long-term potentiation | ||||
| Retrograde endocannabinoid signaling | ||||
| Glutamatergic synapse | ||||
| Huntington's disease | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||
| Metabotropic glutamate receptor group III pathway | ||||
| Metabotropic glutamate receptor group I pathway | ||||
| Endogenous cannabinoid signaling | ||||
| Reactome | G alpha (q) signalling events | |||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| WikiPathways | Hypothetical Network for Drug Addiction | |||
| GPCRs, Class C Metabotropic glutamate, pheromone | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | mGlu5 negative allosteric modulators: a patent review (2013 - 2016).Expert Opin Ther Pat. 2017 Jun;27(6):691-706. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.