Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0X0NV
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| Drug Name |
US9453017, 2
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| Synonyms |
SCHEMBL14833317; CHEMBL3947795; BDBM247410; US9453017, 2
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H29BrN4O2
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| Canonical SMILES |
CC(CN1CCC(CC1)N2C3=C(C=C(C=C3)Br)NC2=O)NC(=O)C4CC4C5=CC=CC=C5
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| InChI |
1S/C25H29BrN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20+,21+/m0/s1
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| InChIKey |
JSVNNLRZCJAYTQ-ZLGUVYLKSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase D1 (PLD1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phospholipase D1 (PLD1) | Target's Patent Info | [1] | |
| BioCyc | Phospholipases | |||
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Ether lipid metabolism | ||||
| Metabolic pathways | ||||
| Ras signaling pathway | ||||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Endocytosis | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Glutamatergic synapse | ||||
| GnRH signaling pathway | ||||
| Pathways in cancer | ||||
| Pancreatic cancer | ||||
| Choline metabolism in cancer | ||||
| Panther Pathway | Angiogenesis | |||
| Ras Pathway | ||||
| Pathway Interaction Database | RhoA signaling pathway | |||
| Arf6 trafficking events | ||||
| CDC42 signaling events | ||||
| Arf6 downstream pathway | ||||
| mTOR signaling pathway | ||||
| ErbB1 downstream signaling | ||||
| IL8- and CXCR1-mediated signaling events | ||||
| Alpha-synuclein signaling | ||||
| Reactome | Role of phospholipids in phagocytosis | |||
| WikiPathways | EGF/EGFR Signaling Pathway | |||
| TSH signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antiviral therapies with phospholipase D inhibitors. US9453017. | |||
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