Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WZ3G
|
|||
| Drug Name |
Entolimod
|
|||
| Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 1 | [1] | |
| Radiation syndrome [ICD-11: NF00; ICD-10: T66; ICD-9: 990] | Phase 1 | [2] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z] | Phase 1 | [1] | ||
| Company |
Cleveland BioLabs Buffalo, NY
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Toll-like receptor 5 (TLR5) | Target Info | Agonist | [1] |
| KEGG Pathway | Toll-like receptor signaling pathway | |||
| Pathogenic Escherichia coli infection | ||||
| Salmonella infection | ||||
| Legionellosis | ||||
| Inflammatory bowel disease (IBD) | ||||
| Reactome | MyD88 deficiency (TLR5) | |||
| IRAK4 deficiency (TLR5) | ||||
| MyD88 cascade initiated on plasma membrane | ||||
| WikiPathways | Toll-like receptor signaling pathway | |||
| MyD88 cascade initiated on plasma membrane | ||||
| Toll-Like Receptors Cascades | ||||
| Pathogenic Escherichia coli infection | ||||
| Regulation of toll-like receptor signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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