Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V6EY
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| Former ID |
DNC001162
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| Drug Name |
Pumiliotoxin 251D
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| Synonyms |
73376-35-9; AC1O5TO7; (+-)-Pumiliotoxin 251D; CHEMBL358960; PTX 251D; 8-Indolizinol, octahydro-8-methyl-6-((2R)-2-methylhexylidene)-, (6Z,8S,8aS)-; C20031
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Investigative | [1] | |
| Company |
Microbiotix
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H29NO
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| Canonical SMILES |
CCCCC(C)C=C1CC(C2CCCN2C1)(C)O
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| InChI |
1S/C16H29NO/c1-4-5-7-13(2)10-14-11-16(3,18)15-8-6-9-17(15)12-14/h10,13,15,18H,4-9,11-12H2,1-3H3/b14-10-/t13-,15+,16+/m1/s1
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| InChIKey |
OKTQTXDNHCOLHT-AJKPHIATSA-N
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| CAS Number |
CAS 73376-35-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase II (TOP2) | Target Info | Inhibitor | [1] |
| Streptococcus Topoisomerase IV A (Stre-coc parC) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73. | |||
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