Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0U6NZ
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| Former ID |
DIB018141
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| Drug Name |
[125I]APNEA
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| Synonyms |
CHEMBL326958; 2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; [3H]N6-2-(4-Aminophenyl)ethyladenosine; AC1L1I2P; AC1Q4Y3F; Lopac0_000118; GTPL417; GTPL462; ChEMBL_198532; SCHEMBL16585344; HMS3260G18; n-[2-(4-aminophenyl)ethyl]-9-pentofuranosyl-9h-purin-6-amine; Tox21_500118; BDBM50037785; LP00118; CCG-204213; NCGC00260803-01; NCGC00093612-03; NCGC00015017-04; NCGC00093612-02; NCGC00093612-01; NCGC00015017-05; NCGC00015017-03; NCGC00015017-02; [3H]N6-2-(4-aminophenyl)ethyladenosine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H22N6O4
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| Canonical SMILES |
C1=CC(=CC=C1CCNC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N
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| InChI |
1S/C18H22N6O4/c19-11-3-1-10(2-4-11)5-6-20-16-13-17(22-8-21-16)24(9-23-13)18-15(27)14(26)12(7-25)28-18/h1-4,8-9,12,14-15,18,25-27H,5-7,19H2,(H,20,21,22)
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| InChIKey |
XTPOZVLRZZIEBW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Agonist | [2] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 462). | |||
| REF 2 | Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7432-6. | |||
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